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CENTRIFUGAL PARTITION CHROMATOGRAPHY CAN GREATLY ENHANCE BOTH YOUR RESEARCH AND PROCESS PRODUCTION
AECS-QuikPrep & ETS Couturier are undoubtedly the World Leaders in
Countercurrent, Centrifugal Partition, Liquid-Liquid Chromatography / Extraction.
We manufacture both Hydrodynamic CCC (Planetary CCC, HSCCC, HPCCC, HPL-LC™) and Hydrostatic CCC (Droplet Centrifugal Partition Chromatography, CPC, HPCPC) at scales from 10 ml to 100+ litres. We have units in both research laboratories and process manufacture units throughout the World. We collaborate with Research Institutes / Universities. Why not contact us to discuss your needs?
We can carry out both Contract Preparation and Feasibility Studies
Have a look at our mini video clip to help your understanding of HPL-LC™, use the buttons on the player to rewind, pause and play.
We can custom build units specific for your requirements because of our unique modular construction. Options of different bore or chamber sizes, different volumes on the same instrument. We can accommodate your specific needs, within your budget. Other competitors cannot match our design and build flexibility. Just ask them and us to custom build to your specific needs and budget. We will custom build to match your requirements. It is most likely our competitors will not custom build, and will instead try to sell an existing model that does not exactly match your needs or budget.
Please contact us by email or call Dr Les Brown on
and he will personally be most happy to answer your questions and explain how we are:-
Totally committed to helping our clients understand and benefit from HPL-LC™
We manufacture both Hydrodynamic CCC (Planetary CCC, HSCCC, HPCCC, HPL-LC™) and Hydrostatic CCC (Droplet Centrifugal Partition Chromatography, CPC, HPCPC) at scales from 10 ml to 100+ litres. We have units in both research laboratories and process manufacture units throughout the World. We collaborate with Research Institutes / Universities. Why not contact us to discuss your needs?
We can carry out both Contract Preparation and Feasibility Studies
Have a look at our mini video clip to help your understanding of HPL-LC™, use the buttons on the player to rewind, pause and play.
We can custom build units specific for your requirements because of our unique modular construction. Options of different bore or chamber sizes, different volumes on the same instrument. We can accommodate your specific needs, within your budget. Other competitors cannot match our design and build flexibility. Just ask them and us to custom build to your specific needs and budget. We will custom build to match your requirements. It is most likely our competitors will not custom build, and will instead try to sell an existing model that does not exactly match your needs or budget.
Please contact us by email or call Dr Les Brown on
and he will personally be most happy to answer your questions and explain how we are:-
Totally committed to helping our clients understand and benefit from HPL-LC™
COUNTER CURRENT CHROMATOGRAPHY: Quattro CCC™ / HPL-LC™ and Partitron HPCPC™
Together AECS-QuikPrep (UK) and ETS Couturier (France) bring you World Leading products for
High Performance Liquid-Liquid Chromatography™ at scales from micro-gram to tonnes per annum
High Performance Liquid-Liquid Chromatography™ at scales from micro-gram to tonnes per annum
• Reduce solvent costs, by 50 to 90% compared to Flash or HPLC Chromatography
• Prepare your targets with no column induced degradation and / or adsorption
• Infinitely polar to infinitely non-polar all obtained in one run
• Offers near infinite number of orthogonal, unique selectivity options
• Optimal scale-up from micro-gram to multiple tonnes per annum
• Solve your solubility problems, massive range of solvents to choose from
• SFC / SFC-MS / MS / MS-MS / HPLC / HPLC-MS compatible
• High mass loading (typically 5 to 40 g per 1000ml capacity)
• Inject up to 10+ % coil volume without excessive band-spreading.
• High pressure (1000psi+) and high “G” (100-150)(250)(350+) options
• Quattro Mk 7 plus Partitron Mk 2: BOTH QUICK (20 to 60+ min)
• Lab unit prices from less than £10,000. Full turnkey process units available
• CONTRACT PREPARATIVE & EXTRACTION SERVICES AVAILABLE. Please contact
• Only manufacturers of both hydrodynamic & hydrostatic CCC in World. Models from 10 ml to 100’s litres capacity. We have process units in daily production.
• Prepare your targets with no column induced degradation and / or adsorption
• Infinitely polar to infinitely non-polar all obtained in one run
• Offers near infinite number of orthogonal, unique selectivity options
• Optimal scale-up from micro-gram to multiple tonnes per annum
• Solve your solubility problems, massive range of solvents to choose from
• SFC / SFC-MS / MS / MS-MS / HPLC / HPLC-MS compatible
• High mass loading (typically 5 to 40 g per 1000ml capacity)
• Inject up to 10+ % coil volume without excessive band-spreading.
• High pressure (1000psi+) and high “G” (100-150)(250)(350+) options
• Quattro Mk 7 plus Partitron Mk 2: BOTH QUICK (20 to 60+ min)
• Lab unit prices from less than £10,000. Full turnkey process units available
• CONTRACT PREPARATIVE & EXTRACTION SERVICES AVAILABLE. Please contact
• Only manufacturers of both hydrodynamic & hydrostatic CCC in World. Models from 10 ml to 100’s litres capacity. We have process units in daily production.
Click to read description of action of HPL-LC™
Quattro HPL-LC™ / HTPrep™ Video
(2 bobbins, 4 coils / 3 coil id’s). Door safety mechanism disabled for this demonstration video. Set spin speeds are very constant. The video judder is caused by camera/internet technology.
Quattro HPL-LC™ / HTPrep™ Video
(2 bobbins, 4 coils / 3 coil id’s). Door safety mechanism disabled for this demonstration video. Set spin speeds are very constant. The video judder is caused by camera/internet technology.
Open your mind, and discover why you need our products?
Researchers & Process Chemists click here for contact information
Do you need help to find targets or to save laboratory / process preparatory costs etc?
Are you planning full spectrum polarity screen for known / unknown targets or novel research for extraction / pre-concentration, or laboratory / process chromatography?
Need more than SFE, SFC, Flash, HPLC, HPLC-MS, can offer? Try CCC / HPL-LC™ / HPCPC
Want to save 50 to 90% solvent costs? Need to stop “on-column” adsorption or degradation causing loss of bio-actives (beneficial or cyto-toxic)? Need orthogonal selectivity? Need total polarity spectrum targets one run? Maximised scale-up success from micro-grams to tonnes / annum? High mass loading (5 to 40g / 1000ml capacity),(10+% coil volume). Rapid prepation times.
Our products can be used for purification of synthetic and natural product targets, enzymes, peptides, proteins, chirals, plus valuable inorganic targets such as radio-nucleotides, precious metals, lanthanides, actinides etc.
Do you need help to find targets or to save laboratory / process preparatory costs etc?
Are you planning full spectrum polarity screen for known / unknown targets or novel research for extraction / pre-concentration, or laboratory / process chromatography?
Need more than SFE, SFC, Flash, HPLC, HPLC-MS, can offer? Try CCC / HPL-LC™ / HPCPC
Want to save 50 to 90% solvent costs? Need to stop “on-column” adsorption or degradation causing loss of bio-actives (beneficial or cyto-toxic)? Need orthogonal selectivity? Need total polarity spectrum targets one run? Maximised scale-up success from micro-grams to tonnes / annum? High mass loading (5 to 40g / 1000ml capacity),(10+% coil volume). Rapid prepation times.
Our products can be used for purification of synthetic and natural product targets, enzymes, peptides, proteins, chirals, plus valuable inorganic targets such as radio-nucleotides, precious metals, lanthanides, actinides etc.
NEW: Coils can be custom made in PTFE, PFA, PEEK, Stainless Steel (S/S) or Titanium. “G”
Force can be Standard (S)(100 to 150G), (H)(250G+) or our new Ultra (U)(300G+). If in your
HPCCC research you need high “G”. Contact us at
Instruments can have coils with, 1, 2, 3 or even 4 different id bores, with pressure abilities of up to 1000+ psi, plus typical “on-column” loadings of 5 to 40 g per 1 litre. You can have customised volumes / bores.
Unique to us, bores available from 1 mm to 30+ mm id, with flows up to multiple litres/min
(Currency Conversion $ x ~1.7, Euro x ~ 1.2, Real x ~ 2.7)(Prices FOB, exclusive taxes)
IntroPrep™ ~140 ml from £9900. Price depending number coils, coil id/volume
l-lcMSPrep™ 30 ml/1mm id bore + ~ 110 ml/2.1mm id bore, both S/S coils, £12900
QuikPrep™ up to ~750 ml, from £10890 depending number coils, coil 1d / volume
HTPrep™ up to ~2000 ml, from £19490, 3 or 4 different coil 1ds / volumes
LabPrep™ up to ~2000ml, from £19490 depending number coils, coil 1d / volume
LabPrepPlus™ ~3000 to ~6000 ml, from £39000 depending number coils, coil id / volume
ProcessPrep™ any volume, 3 to 100’s litres. Coil material always affects price.
Instruments can have coils with, 1, 2, 3 or even 4 different id bores, with pressure abilities of up to 1000+ psi, plus typical “on-column” loadings of 5 to 40 g per 1 litre. You can have customised volumes / bores.
Unique to us, bores available from 1 mm to 30+ mm id, with flows up to multiple litres/min
(Currency Conversion $ x ~1.7, Euro x ~ 1.2, Real x ~ 2.7)(Prices FOB, exclusive taxes)
IntroPrep™ ~140 ml from £9900. Price depending number coils, coil id/volume
l-lcMSPrep™ 30 ml/1mm id bore + ~ 110 ml/2.1mm id bore, both S/S coils, £12900
QuikPrep™ up to ~750 ml, from £10890 depending number coils, coil 1d / volume
HTPrep™ up to ~2000 ml, from £19490, 3 or 4 different coil 1ds / volumes
LabPrep™ up to ~2000ml, from £19490 depending number coils, coil 1d / volume
LabPrepPlus™ ~3000 to ~6000 ml, from £39000 depending number coils, coil id / volume
ProcessPrep™ any volume, 3 to 100’s litres. Coil material always affects price.
Model Type / Volumes / Retail Price Hydrodynamic Countercurrent Chromatography
(CCC / HSCCC / HPCCC / HPL-LC™)
Summary
Do you face a challenge with micro, laboratory or process scale of solid-liquid chromatography / extraction or sample preparation? Need more than SPE, Flash Chromatography, HPLC or HPLC-MS, SFC or SFC-MS, SFE can offer? Click to contact us now to discuss your hydrodynamic and / or hydrostatic L-LC / CCC / CPC needs.
Is your challenge on-column adsorption or on-column degradation? Are your laboratory / process SPE, Flash Chromatography / HPLC / SFC / SFE phase costs / solvent costs too high? Do you have unexplained loss of bioactivity, be that beneficial or cyto-toxicity? Need to obtain all compounds, from infinity polar / non-polar in one run? Do you wish to prepare Active Product Ingredients (API’s), proteins / peptides / enzymes / chirals / macro-molecules such as engine oil additives / polysaccharides / tannins / humic acids or even as yet totally unknown targets / backbone structures ?
WE HAVE COMMERCIAL EXPERIENCE OF ALL OF ABOVE (unpublished as carried out
confidentially for clients).
All above problems can be solved with Liquid-Liquid Chromatography / Extraction solutions unique to us. Our just released modular, Quattro Mk 7, High Performance Liquid-Liquid Chromatography™ / Extraction™ (HPL-LC™/ HPL-LE™) and Partitron HPCPC™ can both work at over 1000 psi, rather 105 psi of historic HSCCC or HPCCC competitors, and function at scales from micro gram to tonnes.
We have over 18 years of commercial Liquid-Liquid Chromatography / Extraction experience creatively solving both academic and industrial research / production problems. Our evolution has now exceeded anyone's expectation based on historic Counter Current / Centrifugal Partition Chromatography, HPCCC perceptions. Why not contact us soon to discuss your requirements for instrumentation or contract preparation?
Do you face a challenge with micro, laboratory or process scale of solid-liquid chromatography / extraction or sample preparation? Need more than SPE, Flash Chromatography, HPLC or HPLC-MS, SFC or SFC-MS, SFE can offer? Click to contact us now to discuss your hydrodynamic and / or hydrostatic L-LC / CCC / CPC needs.
Is your challenge on-column adsorption or on-column degradation? Are your laboratory / process SPE, Flash Chromatography / HPLC / SFC / SFE phase costs / solvent costs too high? Do you have unexplained loss of bioactivity, be that beneficial or cyto-toxicity? Need to obtain all compounds, from infinity polar / non-polar in one run? Do you wish to prepare Active Product Ingredients (API’s), proteins / peptides / enzymes / chirals / macro-molecules such as engine oil additives / polysaccharides / tannins / humic acids or even as yet totally unknown targets / backbone structures ?
WE HAVE COMMERCIAL EXPERIENCE OF ALL OF ABOVE (unpublished as carried out
confidentially for clients).
All above problems can be solved with Liquid-Liquid Chromatography / Extraction solutions unique to us. Our just released modular, Quattro Mk 7, High Performance Liquid-Liquid Chromatography™ / Extraction™ (HPL-LC™/ HPL-LE™) and Partitron HPCPC™ can both work at over 1000 psi, rather 105 psi of historic HSCCC or HPCCC competitors, and function at scales from micro gram to tonnes.
We have over 18 years of commercial Liquid-Liquid Chromatography / Extraction experience creatively solving both academic and industrial research / production problems. Our evolution has now exceeded anyone's expectation based on historic Counter Current / Centrifugal Partition Chromatography, HPCCC perceptions. Why not contact us soon to discuss your requirements for instrumentation or contract preparation?
Click on either thumbnail of the Quattro CCC (above) or one of the two Partitron HPCPC brochures (below) to read full brochure content.
NEW: Sun rotors can be custom made in Stainless Steel or Titanium (for proteins etc).
Instruments can have, 1 or 2 different id bores, with pressure abilities of 1000+ psi, with typically “on-column” loadings of 5 to 40 g per 1 litre. Ideal for proteins, peptides & enzymes.
Unique to us, bores available from 4 mm to 22+ mm id, with flows up to multiple litres/min
(Currency Conversion $ x ~1.7, Euro x ~ 1.2, Real x ~ 2.7)(Prices FOB, exclusive taxes)
QuikPrep HPCPC™ ~1100 ml, from £25990
Options of 4 mm or 6 mm bore chambers
LabPrep HPCPC™ ~2000ml, from £35490
Options of 4 mm or 6 mm or 10 mm bore chambers
LabPrepPlus HPCPC™ ~4000 ml, from £49990
Options of 4 mm or 6 mm or 10 mm bore chambers
Partitron HPCPC™ titanium rotor, in 25,000 ml (25 litre) modules. Multitudes up to any volume, even to 100’s litres. 22 mm bore chambers. From £350000
Instruments can have, 1 or 2 different id bores, with pressure abilities of 1000+ psi, with typically “on-column” loadings of 5 to 40 g per 1 litre. Ideal for proteins, peptides & enzymes.
Unique to us, bores available from 4 mm to 22+ mm id, with flows up to multiple litres/min
(Currency Conversion $ x ~1.7, Euro x ~ 1.2, Real x ~ 2.7)(Prices FOB, exclusive taxes)
QuikPrep HPCPC™ ~1100 ml, from £25990
Options of 4 mm or 6 mm bore chambers
LabPrep HPCPC™ ~2000ml, from £35490
Options of 4 mm or 6 mm or 10 mm bore chambers
LabPrepPlus HPCPC™ ~4000 ml, from £49990
Options of 4 mm or 6 mm or 10 mm bore chambers
Partitron HPCPC™ titanium rotor, in 25,000 ml (25 litre) modules. Multitudes up to any volume, even to 100’s litres. 22 mm bore chambers. From £350000
Model Type / Volumes / Retail Price Hydrostatic CCC, Droplet Centrifugal Partition
Chromatography (CPC / HPCPC )
The AECS-QuikPrep’s collaboration with ETS Couturier, brings you both talent and
stability. Both Company groups have been trading as single family owned Companies for
approximately 30 years.
Since 1983 AECS has been doing research for third party instrument companies, including the design of moving belt HPLC-MS, HPLC-FID and HPLC-MPD detectors; evaporative light scatter detectors; the world's first peltier HPLC column air ovens / chillers, etc. AECS has also helped HPLC Column Companies create completely new HPLC column / phase product lines. These HPLC column / phase products include novel aqueous normal HPLC and Flash Chromatography phases, plus chiral HPLC and Flash / SFC phases.
In addition AECS has built numerous prototype instruments for Blue Chip International Pharmaceutical and Agrochemical Companies.
AECS built our first Quattro CCC™ in the early 1990's, when Smith Kline Beecham were not prepared to purchase the then existing CCC instrumentation, which they considered unsafe; and placed an open design Purchase Order with AECS for what became the Quattro CCC™ Mk I. They like many others, before and since, trusted AECS's design expertise, and contracted AECS to build an improved design with regard both safety and performance. Since then we have designed numerous custom Quattro CCC™ and other concepts of instrumentation for many clients.
Our Group has million plus Euro turnover. We have in-house both design offices and extremely sophisticated, state of art, large scale, specialist multi axis CNC machining (see slide show)(see in house multi-axis machining of large scale titanium rotor), plus a diversified product and customer base.
We offer commercial client proven units, with over 17 years of countercurrent chromatography commercial trading. We sell CCC / HSCCC / HPCCC/ HPL-LC™ / CPC / HPCPC from microgram (l-lcMSPrep) scalable to tonnes per annum, with our very large process scale HPCPC, titanium rotor unit, which is available with any number of 25 litre modules, in one cohesive instrument; the unique Partitron HPCPC™.
Since 1983 AECS has been doing research for third party instrument companies, including the design of moving belt HPLC-MS, HPLC-FID and HPLC-MPD detectors; evaporative light scatter detectors; the world's first peltier HPLC column air ovens / chillers, etc. AECS has also helped HPLC Column Companies create completely new HPLC column / phase product lines. These HPLC column / phase products include novel aqueous normal HPLC and Flash Chromatography phases, plus chiral HPLC and Flash / SFC phases.
In addition AECS has built numerous prototype instruments for Blue Chip International Pharmaceutical and Agrochemical Companies.
AECS built our first Quattro CCC™ in the early 1990's, when Smith Kline Beecham were not prepared to purchase the then existing CCC instrumentation, which they considered unsafe; and placed an open design Purchase Order with AECS for what became the Quattro CCC™ Mk I. They like many others, before and since, trusted AECS's design expertise, and contracted AECS to build an improved design with regard both safety and performance. Since then we have designed numerous custom Quattro CCC™ and other concepts of instrumentation for many clients.
Our Group has million plus Euro turnover. We have in-house both design offices and extremely sophisticated, state of art, large scale, specialist multi axis CNC machining (see slide show)(see in house multi-axis machining of large scale titanium rotor), plus a diversified product and customer base.
We offer commercial client proven units, with over 17 years of countercurrent chromatography commercial trading. We sell CCC / HSCCC / HPCCC/ HPL-LC™ / CPC / HPCPC from microgram (l-lcMSPrep) scalable to tonnes per annum, with our very large process scale HPCPC, titanium rotor unit, which is available with any number of 25 litre modules, in one cohesive instrument; the unique Partitron HPCPC™.
Commercial & Scientific Advantages Compared to Competitors
Scale-up Advantages Compared to Competitors
Modular design, and the use of interchangeable components is common in aerospace, car, electronics etc industry. But only AECS-QuikPrep and ETS Couturier have employed this concept to countercurrent chromatography. We did to ensure success in scale-up..
Modular design, and the use of interchangeable components is common in aerospace, car, electronics etc industry. But only AECS-QuikPrep and ETS Couturier have employed this concept to countercurrent chromatography. We did to ensure success in scale-up..
What is Counter Current Chromatography / Centrifugal Partition Chromatography /
High Performance Liquid – Liquid Chromatography™ / High Performance Liquid –
Liquid Extraction™ ?
How would they help you?
Please click on this link to read our recent review article
Please click on this link to read our recent review article on the 25 Litre Partritron HPCPC™
Please click on the link Why Use CCC and CCC is Compatible with HPLC to see usage and HPLC comparisons.
How would they help you?
Please click on this link to read our recent review article
Please click on this link to read our recent review article on the 25 Litre Partritron HPCPC™
Please click on the link Why Use CCC and CCC is Compatible with HPLC to see usage and HPLC comparisons.
Please consider visiting our newly established
liquid-liquid chromatography / extraction
facility at Reading, near London’s
Heathrow Airport, UK.
Please consider requesting Dr Leslie Brown and /or Dr Rodolphe Margraff visiting you to discuss your larger scale process needs.
Please consider requesting Dr Leslie Brown and /or Dr Rodolphe Margraff visiting you to discuss your larger scale process needs.
If you are interested in collaborative
research, please suggest a topic. We are
particularly interested in high pressure SFE
/ SFC / SFC-MS / L-LC direct to MS
applications, but have a general interest in
many subjects from trace to process quantities.
For example, 21-litre ProcessPrep™ unit start from £190000. Why pay £400,000 or over for
inflexible smaller volume, 18 litre competitors’ process units? Modular Quattro HPL-LC of 3 to 6
litres allows you to start your process chromatography or extraction with a £49000+ first unit
and add capacity only as required. Why not have different bobbins sets with different bores /
volumes for different requirements? All possible with Quattro Hydrodynamic HPL-LC™.
New Quattro HPL-LC™ Mk 7 typical sample preparation times are only 20 to 60+ minutes. Solvent usage for same mass injected can be up to 90% less than Flash or HPLC, and also 40 to 90% less than many CCC / HSCCC / HPCCC / CPC / HPCPC competitors (contact us for details).
We do not have a limited number of fixed instrument choices, as do all our competitors. Our unique modular design means that you can have an instrument custom made to your needs and budget.
Special Promotion Offer: Money with Order a Discount of £1200 Worth of Accessories
New Quattro HPL-LC™ Mk 7 typical sample preparation times are only 20 to 60+ minutes. Solvent usage for same mass injected can be up to 90% less than Flash or HPLC, and also 40 to 90% less than many CCC / HSCCC / HPCCC / CPC / HPCPC competitors (contact us for details).
We do not have a limited number of fixed instrument choices, as do all our competitors. Our unique modular design means that you can have an instrument custom made to your needs and budget.
Special Promotion Offer: Money with Order a Discount of £1200 Worth of Accessories
Considering Countercurrent Chromatography Scale-up? Read below.
If not skip to next box.
If not skip to next box.
For example, large capacity 25-litre Partitron HPCPC™ TITANIUM ROTOR unit start from only
£350000. Why pay £400000 or over for inflexible smaller volume 18 litre inferior PFA or
Stainless Steel competitors’ process units? Modular Partitron HPCPC™ 25 litres allows you to
start your very large scale process chromatography or extraction with a £350000+ first unit
and add capacity only as required. Why not have different rotor sets with different bores /
volumes for different requirements? All possible with our centrifugal partition chromatography
range. Our typical sample preparation times are only 20 to 60+ minutes. Solvent usage for
same mass injected can be up to 90% less than Process Flash or Process HPLC
Partitron HPCPC™ are the only 25 litre titanium rotor HPCPC (High Performance Centrifugal Partition Chromatography) units currently in constant industrial scale of PROTEIN PRODUCTION IN THE WORLD (contact us for details). Many of our competitors only have units where their parent academic University / Research Institute shareholders obtained grants for “one-off” builds. We have industrial process units in daily use, for several years.
We have a proven industrial process scale track record, unlike competitors’, mainly academic projects.
Partitron HPCPC™ are the only 25 litre titanium rotor HPCPC (High Performance Centrifugal Partition Chromatography) units currently in constant industrial scale of PROTEIN PRODUCTION IN THE WORLD (contact us for details). Many of our competitors only have units where their parent academic University / Research Institute shareholders obtained grants for “one-off” builds. We have industrial process units in daily use, for several years.
We have a proven industrial process scale track record, unlike competitors’, mainly academic projects.
Considering Centrifugal Partition Chromatography Scale-up? Read below.
If not skip to next box.
If not skip to next box.
Why don't you utilise Dr Leslie Brown's and Dr Rodolphe Margraff's experience to
help you?
Dr Rodolphe’ Margraff and Dr Leslie Brown both have extensive commercial experience in laboratory CCC, HSCCC, HPCCC, HPL-LC™, plus CPC and HPCPC. They have scale-up experience from laboratory to the process Partitron HPCPC™ etc which will stand you in a highly favoured position, when you move to potentially multiple tonnes per annum GMP production. The Quattro CCC™ / HPL-LC™ are respected quality products, with clients throughout the World. Our unique high backpressure capability will facilitate your HPLC-MS, SFE, SFC, SFC-MS research / process production.
Dr Rodolphe’ Margraff and Dr Leslie Brown both have extensive commercial experience in laboratory CCC, HSCCC, HPCCC, HPL-LC™, plus CPC and HPCPC. They have scale-up experience from laboratory to the process Partitron HPCPC™ etc which will stand you in a highly favoured position, when you move to potentially multiple tonnes per annum GMP production. The Quattro CCC™ / HPL-LC™ are respected quality products, with clients throughout the World. Our unique high backpressure capability will facilitate your HPLC-MS, SFE, SFC, SFC-MS research / process production.
Centrifugal Partition (Hydrostatic CCC) Chromatography
Quattro and Partitron Hydrostatic CCC models (historically called high performance centrifugal partition chromatography) offer the options of 4 / 6 or 10 mm bores in laboratory units, plus over 20 mm bores for the 25 litre capacity Partitron HPCPC™. We uniquely offer more than one bore on a rotor. These instruments are ideally suited to all requirements requiring slow settling biphasic solvents, such as aqueous / aqueous (PEG or Dextran) mixes, or alternatively certain butanol containing mixes. Typical applications would be protein, peptide, enzyme production. To facilitate the above, PTFE or titanium rotors are offered for situations where the sole choice of stainless steel rotors of our competitors, are unsuitable.
Quattro and Partitron Hydrostatic CCC models (historically called high performance centrifugal partition chromatography) offer the options of 4 / 6 or 10 mm bores in laboratory units, plus over 20 mm bores for the 25 litre capacity Partitron HPCPC™. We uniquely offer more than one bore on a rotor. These instruments are ideally suited to all requirements requiring slow settling biphasic solvents, such as aqueous / aqueous (PEG or Dextran) mixes, or alternatively certain butanol containing mixes. Typical applications would be protein, peptide, enzyme production. To facilitate the above, PTFE or titanium rotors are offered for situations where the sole choice of stainless steel rotors of our competitors, are unsuitable.
Countercurrent (Hydrodynamic CCC) Chromatography
All Quattro Hydrodynamic CCC models share the same planet & sun radii, beta values, speed / “G” Force options. We will now guarantee in writing the scale-up for any given bore, by increase in coil length / volume. In the vast majority of cases predictable scale-up occurs for different bore id’s as well. But rare exceptions occur even when you maintain all key design parameters. Our almost 20 years of experience suggests the more key design parameters you change, more scale-up failures occur, irrespective of constant “G” force. We challenge anyone to dispute this statement. Occasional scale-up failures that we experience are no different to occasional scale-up exceptions that occur in Process HPLC / Flash Chromatography for certain target / matrix / phase combinations
But uniquely to us, we recognise this and give you lower-cost laboratory scale Quattro LabPrepPlus™ units that can be used for full process scale testing at bores up to 30+ mm. No competitor gives you lab-scale units to test process-scale bore id’s etc. Do you believe competitors’ suggestions based on very limited Arizona / HEMWat / GUESS mixture solvent / target choices, that their instrument designs, with mini-units ranging from cotton reel sized bobbins rotating at ~2000 rpm, will behave chromatographically the same as maxi-units which you could stand inside rotating at ~800 rpm, simply because “G” Force is the same at 240G, for all target / matrix / biphasic solvent systems? No? Nor do we. We also believe HEMWat has limited applications, excepting restricted polarity pharmaceuticals, they misleading show. They say 90+% their preparations use HEMWat. We say HEMWat useless for most proteins, many peptides, many enzymes, very many natural products / synthetic mixtures. Your views?
Our genuine, experimentation proven knowledge is based on our almost 20 years of CCC / HSCCC / HPCCC / CPC / HPCPC / HPL-LC experience. Please ask competitors, to back their potentially misleading claims by guaranteeing to you their scale-up for all targets / matrices / biphasic systems in writing. What happens when you buy a competitors’ £400000+ / 18+ litre / 10 mm id bore process unit and scale up fails? Would it be cost-effective to optimise a method on such an expensive unit?. Contact us at
All Quattro Hydrodynamic CCC models share the same planet & sun radii, beta values, speed / “G” Force options. We will now guarantee in writing the scale-up for any given bore, by increase in coil length / volume. In the vast majority of cases predictable scale-up occurs for different bore id’s as well. But rare exceptions occur even when you maintain all key design parameters. Our almost 20 years of experience suggests the more key design parameters you change, more scale-up failures occur, irrespective of constant “G” force. We challenge anyone to dispute this statement. Occasional scale-up failures that we experience are no different to occasional scale-up exceptions that occur in Process HPLC / Flash Chromatography for certain target / matrix / phase combinations
But uniquely to us, we recognise this and give you lower-cost laboratory scale Quattro LabPrepPlus™ units that can be used for full process scale testing at bores up to 30+ mm. No competitor gives you lab-scale units to test process-scale bore id’s etc. Do you believe competitors’ suggestions based on very limited Arizona / HEMWat / GUESS mixture solvent / target choices, that their instrument designs, with mini-units ranging from cotton reel sized bobbins rotating at ~2000 rpm, will behave chromatographically the same as maxi-units which you could stand inside rotating at ~800 rpm, simply because “G” Force is the same at 240G, for all target / matrix / biphasic solvent systems? No? Nor do we. We also believe HEMWat has limited applications, excepting restricted polarity pharmaceuticals, they misleading show. They say 90+% their preparations use HEMWat. We say HEMWat useless for most proteins, many peptides, many enzymes, very many natural products / synthetic mixtures. Your views?
Our genuine, experimentation proven knowledge is based on our almost 20 years of CCC / HSCCC / HPCCC / CPC / HPCPC / HPL-LC experience. Please ask competitors, to back their potentially misleading claims by guaranteeing to you their scale-up for all targets / matrices / biphasic systems in writing. What happens when you buy a competitors’ £400000+ / 18+ litre / 10 mm id bore process unit and scale up fails? Would it be cost-effective to optimise a method on such an expensive unit?. Contact us at
AECS & ETS Personnel Pics
Our Engineering Scientists : Pierre-Henri Garret,
MD of ETS Couturier, Robin Self, Head Engineering
AECS-QuikPrep Ltd
Our Lead Scientists : Dr Les Brown, MD of
AECS-QuikPrep Ltd & Dr Rodolphe Margraff,
Designer & Founder of Partitron HPCPC
Your 1st Choice for Preparative and Process Chromatography / Extraction
OUR NEWS BOX
Dr Leslie Brown appointed Visiting Research Fellow at University of Reading
AECS-QuikPrep Ltd begins its second HPLLC based Anti-Malaria Collaborative Research Project.
New Mk 7 Quattro HPL-LC™ released
New Partitron HPCPC™ Mk 2 released. Modular to HUNDREDS OF LITRES capacity
Dr Leslie Brown appointed Visiting Research Fellow at University of Reading
AECS-QuikPrep Ltd begins its second HPLLC based Anti-Malaria Collaborative Research Project.
New Mk 7 Quattro HPL-LC™ released
New Partitron HPCPC™ Mk 2 released. Modular to HUNDREDS OF LITRES capacity
Highly Specialist Titanium Multi-Dimensional
Machining of 25 Litre Rotor which was designed by,
and is machined by ourselves
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on left for "INTRODUCTION" slide show scientific presentation
on left for "INTRODUCTION" slide show scientific presentation
Click on picture on
left for "Quattro
CCC™ WINE
Research" slide
show scientific
presentation
Click on picture on
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CCC™ NEEM
Research" slide
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presentation
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applications slides
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comments
sections)
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applications slides
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Anti-Oxidant
Research
application slides
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comparison
Solid-Liquid and
Liquid-Liquid
Chromatography